دوره 20، شماره 24 - ( 12-1401 )
جلد 20 شماره 24 صفحات 56-43 |
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Barzegari A, Naghibi S, Safayi S, Dashti Khovidaki M, Salehi A. Compare of Two Aerobic Training Methods on SOD and TNF-α levels in the Heart Tissue of Type 2 Diabetic Rats. RSMT 2023; 20 (24) :43-56
URL: http://jsmt.khu.ac.ir/article-1-536-fa.html
URL: http://jsmt.khu.ac.ir/article-1-536-fa.html
برزگری علی، نقیبی سعید، صفایی سمانه، دشتی خویدکی محمدحسن، صالحی آناهیتا. مقایسه دو شیوه تمرین هوازی بر سطوح SOD و TNF-α در بافت قلب رت های مبتلا به دیابت نوع دو. پژوهش در طب ورزشی و فناوری. 1401; 20 (24) :43-56
دانشگاه پیام نور ، ali_barzegari@pnu.ac.ir
چکیده: (1949 مشاهده)
هدف از این مطالعه مقایسه دو شیوه تمرین هوازی بر سطوح SOD وTNF-α در بافت قلب رت های مبتلا به دیابت صورت گرفت. 40 سر رت نر نژاد ویستار ده هفته‌ای به صورت تصادفی در چهار گروه 10 تایی کنترل سالم، دیابت، دیابت+MIT و دیابت+HIT قرار گرفتند. گروه تمرینی شدت متوسط، 5 جلسه در هفته به مدت 8 هفته روی نوارگردان به مدت 60 دقیقه و با سرعت 25 متر در دقیقه و گروه تمرینی شدت بالا نیز 5 جلسه در هفته به مدت 8 هفته با زمان تمرین 60 دقیقه و با سرعت 34 متر در دقیقه دویدند. بافت قلب رت ها جهت تعیین میزان تغییرات SOD و TNF-α با استفاده از روش الایزا مورد بررسی قرار گرفت. جهت بررسی تفاوت بین گروهی متغیرها از آزمون های آماری تحلیل واریانس یک طرفه و تعقیبی توکی در سطح معناداری 05/0≥P استفاده شد. نتایج نشان داد که اختلاف معناداری در سطوح TNF-α و SOD بافت قلب رت¬ها میان چهار گروه پژوهش وجود داشت(001/0P≤ ) میزان سطوح TNF-α در گروه تمرینیHIT نسبت به گروه دیابتی نیز کاهش معناداری را نشان داد(001/0= P) در صورتی که این تغییرات در گروه تمرینیMIT نسبت به گروه دیابت کاهش غیرمعنادار بوده است (117/0= P) میزان سطوح SOD میان گروه های تمرینی MITوHIT نسبت به گروه دیابتی نیز افزایش معناداری را نشان دادند (001/0= P). به نظر می رسد، تمرینات هوازی با شدت های مختلف سبب بهبود سطوح SOD و TNF-α می شود، گرچه شدت تمرین در تمرینات تناوبی عامل موثری در تغییرات سطوح هر دو متغیر بوده است.
نوع مطالعه: پژوهشي |
موضوع مقاله:
فیزیولوژی ورزشی
دریافت: 1401/7/10 | پذیرش: 1401/12/15 | انتشار: 1401/12/15
دریافت: 1401/7/10 | پذیرش: 1401/12/15 | انتشار: 1401/12/15
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