The aim of this study was to present an exploratory model to express the relationships between a set of factors including personality factors, attachment styles, control source, coping strategies and perceived stress and disease perception in patients with hemophilia, emphasizing the mediating role of social exchange styles. The present study is a correlational study based on path analysis. In order to conduct the study, 450 patients from the Hemophilia Support Centre in Isfahan were randomly selected. The instruments used in this study included the Neo Five Personality Factor Questionnaire, the Hazen and Shaver Attachment Styles Scale, the Rutter Control Scale, the Andler and Parker Stress Coping Questionnaire, the Cohen Perceived Stress Questionnaire, the Disease Perception Questionnaire and the Libman Social Learning Exchange Questionnaire. The results indicated a linear relationship between a group of factors such as neurotic personality traits, responsibility, extraversion and flexibility, two coping styles (emotion-oriented, problem-oriented and avoidance) and a secure attachment style and disease perception. The results also showed personality traits (neuroticism, extraversion, pleasantness, flexibility and responsibility), coping styles (avoidance and emotion-oriented), attachment style (safe and unsafe ambivalent) and source of control are related to the perception of disease through the mediating role of social exchange style fairness. Therefore, in order to provide measures to improve the perception of patients with hemophilia, it is necessary to pay special attention to personality traits, coping styles, attachment style, source of control and perceived stress in addition to fair social exchange styles.
