Dr Fatemeh Kazeminasab, Mr Mohammad Hossein Mahboobi, Dr Karim Azali Alamdari,
Volume 0, Issue 0 (11-2019)
Abstract
Exercise training and vegetarian diets have been accepted as suitable and non-pharmacological methods to weight loss, and improve cardiovascular factors such as blood pressure. The purpose of this study was to investigate the impact of combining aerobic exercise (AE) and vegetarian diet (VD) on blood pressure and body weight in adults with overweight and obesity. The PubMed, Web of Science, Scopus, and Google scholar databases were searched until February 2023 for English articles, and 1065 articles were found. Meta-analyses were performed to compare the impact of aerobic exercise and vegetarian diet on body weight, blood pressure in adults with overweight and obesity. Data analysis was performed using random effect model and weighted mean differences (WMD). Also, the confidence interval of 95% was considered. Also, the I2 test was used to determine heterogeneity, and the Funnel plot and Egger tests at a significant level of 0.1 were used to determine publication bias. The results of meta-analysis of 25 studies with 10192 adults showed that combined aerobic exercise and vegetarian diet significantly decreased in body weight [WMD=-4.63, (CI: -5.7 to -3.56), p=0.001], systolic blood pressure [WMD=-6.94, (CI: -7.86 to -6.01), p=0.001], and diastolic blood pressure [WMD=-4.5, (CI: -5.04 to -3.96), p=0.001], in adults with overweight and obesity. The findings of the present meta-analysis suggest aerobic training alongside vegetarian diet as a non-medication approach for weight loss and blood pressure control in adults with overweight and/or obesity. In addition, aerobic exercise and vegetarian diet with both types of duration (less than 12 weeks and more than 12 weeks) cause a significant decrease in blood pressure in adults with obesity and overweight.
Elham Shahabpoor, Mohammad Amin Delavari,
Volume 21, Issue 26 (12-2023)
Abstract
Cachexia syndrome and the risk of cardiovascular diseases are highly prevalent in cancer patients.The purpose of the present study was to investigate the effect of endurance training as a therapeutic method on muscle cachexia and cardiovascular consequences caused by breast cancer. After 2 weeks of breast cancer induction, 20 BALB/c mice (age: 6-8 weeks and weight: 17- 18 g) mice performed the maximum aerobic capacity test and were randomly allocated into tumor-control and tumor-exercise groups. The tumor-exercise group performed the endurance Training protocol for 6 weeks, 5 days a week with gradual increase in intensity from 12 to 20 (m.min-1) and duration from 25 to 55 minutes And 24 hours after the last training session, the maximum aerobic capacity test was performed. 48 hours after the last training session, the mice were sacrificed. Heart weight, weight of gastrocnemius and soleus muscle, heart mass index, ratio of weight of soleus muscle to body weight and ratio of weight of gastrocnemius muscle to body weight were measured in tumor-control and tumor-exercise groups. Data were analyzed by independent t-test at the significance level of P≥0.05. The results of the present study showed a significant increase in heart weight (P=0.005), spleen weight (P=0.029), weight of the gastrocnemius muscle (P=0.009) and soleus muscle (P=0.022) in the tumor-exercise group compared to the tumor-control group. Also, significant increase in the heart mass index (P=0.016) and the ratio of the weight of the gastrocnemius muscle to the body weight (P=0.005) and the ratio of the soleus muscle to the body weight (P=0.021) were observed in the tumor-exercise group compared to the tumor-control group. In conclusion,Endurance training seems to be a potential treatment method and strategy to improve the health of the skeletal muscle and cardiovascular system and reduce the process of muscle cachexia caused by breast cancer.
