Showing 9 results for Aerobic Exercise
Ssaeedeh Shiri Lord, Roghayeh Fakhrpour, Karim Azali Alamdari,
Volume 0, Issue 0 (11-2019)
Abstract
Background and Purpose; Sarcopenia is a progressive and generalized skeletal muscle disorder that involves rapid loss of muscle mass and function. The purpose of this study was to investigate the effect of continuous aerobic exercise on sarcopenia, changes in myofibrils in skeletal muscle and exercise performance in elderly rats with Alzheimer's disease, to investigate the effect of physical activity on reducing sarcopenia and changes in myofibrils in skeletal muscle and exercise performance in elderly rats with Alzheimer's should be measured.
Materials and Methods; In the present study, 40 aged Wistar rats with an average weight of 300 grams. The rats were randomly divided into four ten groups including control patient, training patient, healthy control, healthy training. The exercise group participated in a six-week continuous aerobic exercise program. The patient group was diagnosed with Alzheimer's disease by intraperitoneal injection of scopolamine for 14 days, and after ensuring the induction of Alzheimer's disease using the novel object recognition test, the training group participated in a six-week continuous aerobic training program.
Results; Based on the results after six weeks of continuous aerobic training, according to the measurement of the tissue components in the soleus and EDL muscles of the healthy group of rats under training, it showed a slight increase in the extent of the tissue parenchyma and the diameter of the muscle fibers compared to the healthy control group, but these changes were not significant. The quantification of the extent of the tissue components in the soleus and EDL muscles of the studied rats showed a significant decrease in the muscle parenchyma and also a significant decrease in the average diameter of the muscle fibers in the patient group compared to the healthy control group (p<0.01). The area of the muscle parenchyma and the average diameter of the soleus and EDL muscle fibers in the mice of the patient group under training compared to the mice of the patient group showed a significant increase in tissue (p<0.05) and the amount of tissue edema and the presence of connective tissue showed a significant decrease (p<0.01 and p<0.05).
Conclusion: According to the findings, it seems that sports activities have positive effects on sarcopenia disease and myofibril changes, as well as the sports performance of rats with Alzheimer's disease.
Keywords: continuous aerobic exercises, Alzheimer's, sarcopenia, muscle myofibril
Background and Purpose; Sarcopenia is a progressive and generalized skeletal muscle disorder that involves rapid loss of muscle mass and function. The purpose of this study was to investigate the effect of continuous aerobic exercise on sarcopenia, changes in myofibrils in skeletal muscle and exercise performance in elderly rats with Alzheimer's disease, to investigate the effect of physical activity on reducing sarcopenia and changes in myofibrils in skeletal muscle and exercise performance in elderly rats with Alzheimer's should be measured.
Materials and Methods; In the present study, 40 aged Wistar rats with an average weight of 300 grams. The rats were randomly divided into four ten groups including control patient, training patient, healthy control, healthy training. The exercise group participated in a six-week continuous aerobic exercise program. The patient group was diagnosed with Alzheimer's disease by intraperitoneal injection of scopolamine for 14 days, and after ensuring the induction of Alzheimer's disease using the novel object recognition test, the training group participated in a six-week continuous aerobic training program.
Results; Based on the results after six weeks of continuous aerobic training, according to the measurement of the tissue components in the soleus and EDL muscles of the healthy group of rats under training, it showed a slight increase in the extent of the tissue parenchyma and the diameter of the muscle fibers compared to the healthy control group, but these changes were not significant. The quantification of the extent of the tissue components in the soleus and EDL muscles of the studied rats showed a significant decrease in the muscle parenchyma and also a significant decrease in the average diameter of the muscle fibers in the patient group compared to the healthy control group (p<0.01). The area of the muscle parenchyma and the average diameter of the soleus and EDL muscle fibers in the mice of the patient group under training compared to the mice of the patient group showed a significant increase in tissue (p<0.05) and the amount of tissue edema and the presence of connective tissue showed a significant decrease (p<0.01 and p<0.05).
Conclusion: According to the findings, it seems that sports activities have positive effects on sarcopenia disease and myofibril changes, as well as the sports performance of rats with Alzheimer's disease.
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Volume 9, Issue 1 (3-2011)
Abstract
Training exercises are known to affect depressed girls condition, but the effect of regular exercise in exhilarating environments, in particularly on markers related to epinephrine metabolism in depressed girls are not well known. The purpose of the present study was to determine effect of the 6 weeks of intermittent walking in water on urine MHPG sulphate and Hamilton scale in the depressed girls. Twenty-four of girls' students, who suffering from moderate depression, randomly divided into exercise and control groups. The subjects in the training group performed the progressive walking exercise of 60-70% of maximal heart rate, 3 times a week and for 6 weeks. The Hamilton scale and urine samples were measured in before and after the mentioned exercise protocol. The urine MHPG sulphate was measured by HPLC-flurometric detection method. The data were analyzed by t- student and the Pearson correlation coefficient tests at p≤0/05 levels. The results showed the 6 weeks of exercise resulted in significant increase in the urine MHPG sulphate and VO2max and significant decrease in Hamilton scale compared to the control group. Furthermore, there was a significantly positive correlation between the urine MHPG sulphate and VO2max (r= 0/65). However, there was a significant reversely correlation (r= - 0/52) between the urine MHPG sulphate and Hamilton scale in prediction of depression. These results emphasize the role of regular physical exercise, particularly in exhilarating environments in the promotion of depression state. Also, in some conditions can be used Hamilton scale instead of the urine MHPG sulphate detects.
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Volume 11, Issue 5 (3-2013)
Abstract
Background and aims:
In many communities, the sport as a method of therapy is used to improve the
disabled and veterans' health which has been a useful and effective. The aim of
this study was to examine the effect of aerobic exercise on general health and
serotonin levels in inactive veterans. Material and method: Based on semi
experimental design 40 veterans, 25 percent impaired and with age average
40/3±1/4, were selected and randomly divided into two experimental and control
groups. Subjects in the experimental group participated in a period of 12 week’s
aerobic exercise training program, which done 3 times a week at 50-65 percent
of Vo2max. Control group did not participate in any exercise program during
study period. General health of the subjects and its subscales was measured by
the General Health Questionnaire (GHQ). Serotonin levels, VO2max, percent
body fat and BMI before and after training for both groups were measured
respectively. Data were analyzed using t-tests at 5% alpha error level was
performed using SPSS version 16. Results: Data analysis showed significant
difference between the two groups in general health. The difference in
psychosomatic subscales, anxiety and insomnia, social dysfunction and
depression were observed between two groups. Also, the results of this study
showed that after 12 weeks aerobic exercise, percent body fat, BMI and lipid
profile decreased significantly in training group. VO2max and serotonin also
increased significantly compared with the control group (p<0.05). Conclusion:
Aerobic exercise for inactive veterans maybe effective in reducing serotonin
levels and increasing general health and placed in line health promotion
programs.
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Volume 12, Issue 7 (4-2014)
Abstract
Introduction: This research aimed to analyze the effect of 12 weeks aerobic exercise training on some
characteristics of immune system and general health of women with breast cancer. Methods: 40 female
with breast cancer, undertaking chemotherapy, were classified in exercise group with mean age of 36/9±13/2
years, weight of 67/2±9/95 kilograms and body mass index of 21/9±2/9 kg/m2 and control group with mean
age of 38/6±10/1 years, weight of 65/1±8/28 kilograms and body mass index of 21/4±2/1kg/m2. Exercise
group Perfored in 12 contionous weeks walking with moderate intensity (based on Modified-Borg scale and
40-60% Maximum Heart rate)/3 times a week/30-45 minutes in each session. General Health Questionnaire
(GHQ) was used for evaluating general health level. Before and after 4, 8 and 12 weeks CBC DIFF test was
conducted for aim of assessing some characteristics of immune system. CANCOVA was used to determine
the pure effect of exercise intervention. The data were analyzed with significant level of p≤0/05 and by SPSS
16. Results: General health and hope of life was decreased significantly after intervention in control group
(p≤0.05). Number of leukocytes of exercise group was higher after the exercise intervention, but this
difference was not significant, but number of leukocytes of control group was decreased significantly
(p≥0.05). Conclusion: Regular aerobic exercise with moderate intensity is an effective way in maintenance
the number of leukocytes, improving immune system and enhancing levels of general health.
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Volume 12, Issue 8 (10-2014)
Abstract
Introduction: The aim of this study was to determine the effect of an eight- week aerobic exercise on some immune system factors in patients with rheumatoid arthritis. Twenty – three women (age: 51.96 ± 7.73, weight: 72.37 ± 10 kg) were enrolled in the study voluntarily Methods: In this quasi – experimental random study, subjects were assigned to training and control group. The training group ( n=12)participated in aerobic exercises with the intensity of 65% reserve heart rate on stationary cycle ergometer three days a week. Both groups received the same medication during the study. Differences between groups were analyzed by independent t – test and differences inside groups were analyzed by dependent t-test. Patients' blood samples were taken before and after training period and the frequency of White blood cells, A
immunoglobulin and lymphocyte were also taken by standard methods. Results: After 8 weeks aerobic exercise, there was a significant decrease in white blood cells, BMI and also a significant increase (P<0/05).in A immunoglobulin and lymphocyte in training group. No significant differences were seen in variables between groups )P>0/05).Conclusion: It seems submaximal aerobic exercise can activate some immune system neutralization processes against damage and phagocyte factors.
M Naghibi,
Volume 17, Issue 17 (4-2019)
Abstract
Osteoporosis is characterized by low bone mineral density resulting into an increased risk of fracture (9). The aim of the study is determine the effect of aerobic exercise with blood flow restriction (BFR) and vitamin D supplementation on ostosis metabolic markers (OMM) among middle aged females. In this study 30 females with age of 42.76±7.44, height of 157.90±5.74, weight of 70.55±9.68 and BMI of 28.33±3.87, divided in three groups of 10 subjects, randomly. Two empirical Groups with and without BFR, both with vitamin D supplementation, one hour before training, performed aerobic exercise during eight weeks, three days a week, one hour a day, with 50 - 70% intensity of maximal heart rate. Density of OMM, calcium, phosphorous and alkaline phosphate examined in lab, 48 hours before and after training period in saving status before breakfast. Aerobic power of empirical groups determined with 12 minutes run/ walking cooper test. For data analysis used descriptive statistics, ANOVA and analysis variance with repeated measures. Results showed that eight weeks exercise with BFR and vitamin D supplementation, the density of calcium and phosphorous increased significantly. The density of Alkaline - phosphate did not show variation significantly. In the other hand, only the rate of calcium showed variation significantly, which increased in without BFR more than others. In conclusion, aerobic exercise with and without BFR and vitamin D supplementation can increase the density of OMM, calcium, phosphorous and alkaline- phosphate. But only the density of calcium showed increasing significantly.
Elahe Talebi-Garakani, Shokoufeh Kheradmand, Khadijeh Nasiri,
Volume 21, Issue 26 (12-2023)
Abstract
The prevalence of obesity in postmenopausal women is higher compared to men. A decrease in estrogen with menopause leads to dysfunction in mitochondria. The purpose of this study is to investigate the effect of high intensity aerobic training(HIT) on the copy number of mitochondrial genome (mtDNAcn) and mitochondrial transcription factor A(Tfam) in visceral adipose tissue(VAT) in ovariectomized(OVX) rats fed with high-fat diet(HFD). 40 rats (8 weeks, 200±20 gr) were divided into 5 groups:1) normal diet (ND), 2) ND+OVX, 3) HFD, 4) HFD+OVX, and 5) HFD+OVX+HIT. HIT performed aerobic training (80-85% of maximum oxygen consumption) for 8 weeks/5 sessions/42 minutes.48 hours after the last training session, VAT samples were taken to evaluate mtDNAcn and Tfam gene expression by qRT-PCR method. ANOVA and LSD tests were used to compare the differences between groups. OVX and HFD didn’t lead to a significant change in Tfam gene expression, but caused a significant decrease in the mtDNAcn compared to the control group. HIT caused a significant increase in Tfam gene expression compared to the control group and Tfam gene expression and mtDNAcn compared to the HFD+OVX. Hence, HIT improves mitochondrial function through mtDNAcn and Tfam gene expression in VAT in OVX rats fed by HFD.
Elmira Ahmadi, Shahnaz Shahrbanian, Mohamadreza Kordi, Reza Gharakhanlou, Gregory Pearcey,
Volume 22, Issue 27 (8-2024)
Abstract
Fatigue is one of the most common symptoms among individuals with multiple sclerosis (MS). The imbalance of inflammatory cytokines in the brain causes mental fatigue. It is believed that aerobic exercise may moderate the level of inflammation of cytokines and thus reduce mental fatigue. This study was conducted to investigate the effect of swimming aerobic training on pro-inflammatory factors (interleukin 6) and anti-inflammatory factors (interleukin 10) to evaluate mental fatigue in the brains of female mice after EAE induction. In this research, 21 mice (8 weeks old, 18 to 20 grams) were divided into three groups: healthy control, EAE control, and EAE swimming aerobic exercise. The animals in the training group performed moderate-intensity swimming exercises for 4 weeks, with 5 sessions per week, each session lasting 30 minutes. The western blot method was used to analyze the research variables. The results showed no significant difference in the amount of IL-6 between the EAE group and the swimming training group, but the amount of IL-10 in the swimming training group showed a significant increase compared to the EAE group. The ratio of IL-10/IL-6 values between the swimming training group and the EAE group was also not significant. It seems that moderate-intensity swimming aerobic exercises, without changing the pro-inflammatory factor, along with increasing the anti-inflammatory factor IL-10, can lead to an improvement in the balance of the inflammatory index and a reduction in fatigue in the EAE group and the swimming exercise group.
Fatemeh Kazeminasab, Mohammad Hossein Mahboobi, Karim Azali Alamdari,
Volume 22, Issue 27 (8-2024)
Abstract
The purpose of this study was to investigate the impact of combining aerobic exercise (AE) and vegetarian diet (VD) on blood pressure and body weight in adults with overweight and obesity. The PubMed, Web of Science, Scopus, and Google scholar databases were searched until February 2023 for English articles, and 1065 articles were found. Meta-analyses were performed to compare the impact of aerobic exercise and vegetarian diet on body weight, blood pressure in adults with overweight and obesity. Data analysis was performed using random effect model and weighted mean differences (WMD). The results of meta-analysis of 25 studies with 10192 adults showed that combined aerobic exercise and vegetarian diet significantly decreased in body weight [WMD=-4.63, p=0.001] , systolic blood pressure [WMD=-6.94, p=0.001] , and diastolic blood pressure [WMD=-4.5, p=0.001] , in adults with overweight and obesity. Aerobic training alongside vegetarian diet as a non-medication approach for weight loss and blood pressure control in adults with overweight and/or obesity. In addition, aerobic exercise and vegetarian diet with both types of duration (less than 12 weeks and more than 12 weeks) cause a significant decrease in blood pressure in adults with overweight and obesity.
