Search published articles


Showing 3 results for Kashef
The effect of acute glutamine supplementation along with intermittent exercise on Hsp70 and blood lactate response of club soccer players
Dr Sajad Karami, Dr Hamid Rajabi, Dr Majid Kashef, Dr Mohammad Ali Gharaat,
Volume 0, Issue 0 (11-2019)
Abstract
Introduction and purpose: The present study was conducted with the aim of investigating the effect of acute glutamine supplementation along with intermittent exercise on Hsp70 and blood lactate response of club football players. Methodology: 32 players of the Tehran Railway team were selected and randomly divided into four groups: control, supplement, supplement-sports activity, and sports-activity. Subjects participated in daily exercises before conducting the study, and only two complementary groups - sports activity and sports activity - performed the periodic protocol. Blood samples were taken at baseline, pre-test, post-test and 90 minutes after the test. The supplement and placebo were consumed in an amount of 0.5 g/kgBW and a volume of 5 ml/kgBW one hour before the periodic protocol. The interval protocol included 3 stages of 20-minute running with an intensity of 80% of the maximum heart rate and a 5-minute rest of walking between the stages. HSP72 and blood lactate levels were measured using ELISA and enzymatic methods, respectively. The data were analyzed using the analysis of variance test with repeated measures and the between-group factor at the P≤0.05 level. Findings: Glutamine supplement alone and together with exercise stimulate the response of HSP72 and the combination of supplement and exercise leads to a greater response of HSP72 and lactate changes did not play a role in this response. Discussion and conclusion: It seem that taking glutamine supplements in the long term creates more adaptations, which of course should be studied.
 
Exercise preconditioning: review
Dr Majid Kashef, Dr Maral Ramez, Azam Ahmadi,
Volume 20, Issue 24 (3-2023)
Abstract
It is estimated that by 2035, more than 130 million adults will suffer from various types of cardiovascular diseases. Therefore, it is very important to know the pathogens of cardiac diseases and investigate new treatments. Also, despite continuous progress in diagnosis, patient education, and risk factor management, myocardial infarction (MI) remains one of the most common causes of morbidity, hospitalization, and mortality worldwide. The events associated with MI are highly complex and characterized by rapid metabolic and biochemical changes. Exercise training is an effective cardioprotective strategy that reduces adverse effects of MI and ischemia/reperfusion (I/R). Multiple signaling pathways of exercise preconditioning in mitigating MI-induced cardiac damage is one of the topics that has attracted much attention. In this article, some of the contributing factors in exercise-induced cardiac protection, including mitochondrial changes, metabolic changes, vascular adaptations, antioxidant capacity, heat shock proteins, cyclooxygenase levels, ATP-sensitive potassium channels, adenosine, protein kinase C, calcium and klotho homeostasis are discussed.
 

The Interactive Effect Of Six Weeks Of Resistance Training And Whey Protein Supplementation On PRAS40 Gene Expression And Muscle Hypertrophy In Male Wistar Race Rats
Fereshteh Shahidi, Hamide Ahmadi, Majid Kashef,
Volume 22, Issue 28 (12-2024)
Abstract
PRAS40 is expressed in all types of body tissues and is present in the muscle growth pathway and has multiple phosphorylation sites. Studies have shown that PRAS40 plays a role in regulating cell growth. The aim of this study was to evaluate the effect of six weeks of resistance training and whey protein supplementation on PRAS40 and biceps hypertrophy in male Wistar rats
Method:This developmental experimental study was carried out in 1402 year. 23 eight-week-old male Wistar rats (250 grams) were randomly divided into three groups: resistance training, resistance training+ supplement, and control. After two weeks of orientation, the training groups completed six weeks of resistance training, climbing the ladder five days a week. The training +supplement group received whey protein (2.05 g/kg dose) through gavage. 48 hours after the last training, a blood sample was taken and the gastrocnemius muscle was removed, frizzed, and saved to evaluate the expression of the PRAS40 gene.
Findings: Six weeks of resistance training with whey supplement caused a significant decrease in PRAS40 gene expression and an increase in body and muscle weight in the exercise and supplement + exercise groups.
Conclusion: The resistance training protocol along with her supplement can lead to muscle hypertrophy and activate the anabolic pathways in the muscle through the suppression of the PRAS40 pathway.

Page 1 from 1     

© 2025 CC BY-NC 4.0 | Research in Sport Medicine and Technology

Designed & Developed by: Yektaweb