دوره 20، شماره 24 - ( 12-1401 )
جلد 20 شماره 24 صفحات 88-68 |
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Kashef M, Ramez M, Ahmadi A. Exercise preconditioning: review. RSMT 2023; 20 (24) :68-88
URL: http://jsmt.khu.ac.ir/article-1-565-fa.html
URL: http://jsmt.khu.ac.ir/article-1-565-fa.html
کاشف مجید، رامز مارال، احمدی اعظم. فعالیت ورزشی و پیش آماده سازی قلب: یک مطالعه مروری. پژوهش در طب ورزشی و فناوری. 1401; 20 (24) :68-88
دانشگاه شهید رجائی
چکیده: (2297 مشاهده)
برآورد شده است که تا سال 2035، بیشتر از 130 میلیون فرد بزرگسال از انواع مختلف بیماری های قلبی عروقی رنج خواهند برد. بنابراین شناخت پاتوژن های بیماری های قلبی و بررسی درمان های جدید بسیار اهمیت دارد. همچنین، علی رغم پیشرفت مداوم در تشخیص بیماری، آموزش بیماران و مدیریت عوامل خطرآفرین، انفارکتوس عضله قلب (MI) یکی از رایج ترین علل ناخوشی، بستری شدن در بیمارستان و مرگ و میر در سطح جهان است. رخ داد های همراه با MI به مقدار زیادی پیچیده است و با تغییرات متابولیکی و بیوشیمیایی سریع مشخص می شود. تمرین ورزشی یک استراتژی موثر برای محافظت از قلب است که اثرات نامطلوب MI و ایسکمی/ خون رسانی مجدد (I/R) را از طریق سازوکاری که پیش آماده سازی ورزشی نامیده می شود،کاهش می دهد. مسیرهای سیگنالینگ متعدد پیش آماده سازی ورزش در کاهش آسیب های قلبی ناشی از MI یکی از موضوعاتی است که توجه بسیاری را به خود جلب کرده است. در این مقاله به برخی از عوامل مشارکت کننده در محافظت قلبی ناشی از ورزش از جمله تغییرات میتوکندریایی، تغییرات متابولیکی، سازگاری های عروقی ، ظرفیت آنتی اکسیدانی، پروتئین های شوک گرمایی، سطح سیکلواکسیژناز، کانال های پتاسیمی حساس به ATP، آدنوزین، پروتئین کیناز C، هموئوستاز کلسیم و کلوتو پرداخته شده است.
نوع مطالعه: پژوهشي |
موضوع مقاله:
فیزیولوژی ورزشی
دریافت: 1401/4/12 | پذیرش: 1401/8/26 | انتشار: 1401/12/15
دریافت: 1401/4/12 | پذیرش: 1401/8/26 | انتشار: 1401/12/15
فهرست منابع
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