Volume 18, Issue 57 (No.1&2-صفحات انگلیسی از 74 تا 82 2004)
2004, 18(57): 137-146 |
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The Effect of Taurine on Toxicity Cadmium on Spermatogenesis in NMRI Mouse. Journal title 2004; 18 (57) :137-146
URL: http://jsci.khu.ac.ir/article-1-1140-en.html
URL: http://jsci.khu.ac.ir/article-1-1140-en.html
Abstract: (5060 Views)
Cadmium is an important environmental pollutant with much application. The main use of this metal is in electroplating and used as a cathode material for nickel cadmium batteries. Chronic exposure to cadmium can result in damaging of various tissues such as the liver, kidney and tested. In this study, we used cadmium chloride at a dose of 2mg/kg, taurine at a dose of 400mg/kg both were used intreperitneal administration for the long-term treatment for 4 weeks (two days in week). The parameters include relative testicular weight, body weight, testicular volume, the thickness of tunca alboginea and spermatogonia A and B, spermatocyte, spermatid, leyding cell and sertoli cellwere investigated. The results indicated that cadmium significantly increased the thickness of tunca alboginea and relative testicular weight, whereas, the other parameters were significantly decreased also no change never observed after treatment with a combination of taurine and cadmium. This results demonstrated that cadmium induced damage was protected by taurne in mice.
Published: 2004/01/15
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