The aim of this study was to investigate the mediating role of five factors personality in regulating of relationship between perceived and objective stress and anxiety, depression, and physical symptoms . 390 bank managers responded five factors personality ( NEO ) , perceived stress , objective stress , anxiety and depression scals and symptoms check list . The results showed the interaction between Neurotism , Extraversion , conscientiousness mediated the relationship of perceived stress with anxiety, depression and physical symptoms . Objective stress influenced by perceived stress that emphasized on importance of subjectivity of stress. Findings showed simultaneous interaction these factors (low Neurotism , high Extraversion , high conscientiousness ) leads to a reduction in the effects of stress .

Keywords: Personality Factors ( Neurotism, Extraversion, Openness to experience, agreeableness, conscientiousness ), perceived stress, objective stress, anxiety, depression, and physical symptoms