"Teaching-Learning Approach" is a model of interaction between teachers and students in an educational environment and one of the main components of the educational system. This model can be organized and designed on the basis of various opinions and ideas, including philosophical or scientific theories. This research aims to design and explain teaching-learning approach based on the complexity paradigm. The complexity paradigm is one of the contemporary scientific approaches that is penetrating into different areas of knowledge such as education. Therefore, in this descriptive-analytical study, based on the concepts and components of the complexity paradigm, the teaching-learning approach is as follows: in teaching-learning approach based on complexity paradigm, the steps and sequence of teacher and student activities are strategic for continuous organization of all learning and teaching processes and activities performed through cooperation of students and the teacher. In other words, the teacher designs and organizes the learning environment in a rich and complex way, leading the student to research and learning; So the student is an active and researcher; A researcher who constantly organizes and reorganizes in interaction with the learning environment and actually learns and develops. Hence, the relationship between teacher and students is dynamic and multifaceted based on the variety and extension of their interactions with each other and environment.